Buy research chemicals Buy URB-597 Online
Buy URB-597 usa Online
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buy URB-597 usa also known as KDS-4103 because is a relatively selective inhibitor of the enzyme fatty acid and so amide hydrolase (FAAH).
FAAH is also the primary degradation enzyme for the endocannabinoid anandamide and, as such, inhibition of FAAH leads to an accumulation of anandamide in the CNS .
and periphery where it activates cannabinoid receptors. URB597 has been found to elevate anandamide levels and have activity against neuropathic pain in a mouse model. URB597 was at one point being developed by Kadmus Pharmaceuticals, Inc. for clinical trials in humans.
Potent and selective fatty acid amide hydrolase (FAAH) inhibitor (IC50 values are 3 and 5 nM in human liver and rat brain, respectively). Exhibits no significant inhibitory activity against a variety of receptors, ion channels and enzymes, including human cannabinoid receptors and rat monoacylglycerol lipase. Displays antiallodynic and antihyperalgesic activity in an inflammatory pain model
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